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Table 1 Summarized comparison of TPEs and experimental data

From: Monte Carlo analysis of an ODE Model of the Sea Urchin Endomesoderm Network

Perturbation

A

B

Hnf6_KD

9/14

0.6429

Otx_KD

1/2

0.5000

FoxA_KD

9/16

0.5625

TBr_KD

4/7

0.5714

Alx1_KD

11/17

0.6471

Gcm_KD

7/11

0.6364

Hox_KD

6/13

0.4615

Bra_KD

8/12

0.6667

Dri_KD

4/16

0.2500

SoxB1_KD

2/5

0.4000

Ets1_KD

2/18

0.1111

Blimp1_KD

3/9

0.3333

Eve_KD

3/8

0.3750

GataE_KD

19/28

0.6786

Snail_KD

2/2

1.0000

FoxB_KD

0/2

0.0000

GataC_KD

0/2

0.0000

Pmar1_KD

0/2

0.0000

Brn_KD

0/2

0.0000

Pmar1_MOE

11/28

0.3929

Alx1_MOE

5/15

0.3333

SoxB1_MOE

7/39

0.1795

total

113/268

0.4216

total KD

90/186

0.4839

total MOE

23/82

0.2805

  1. Agreement between experimental data and topological perturbation effects. Column A lists matches and total experimental data points, column B indicates the percentage of matches. The last three lines indicate results for all perturbations, for all knockdown perturbations and for all MOE perturbations.