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Table 2 Nominal electrochemical characteristics of subcellular environments in eukaryotes. Values refer to yeast cells unless noted otherwise.

From: Calculation of the relative metastabilities of proteins in subcellular compartments of Saccharomyces cerevisiae

Environment

Eh, volt

pH

log m

Extracellular (intestine)

-0.137 to -0.80a

3g

-83.3 to -79.4

Cytoplasm

-0.235 to -0.222b

6.5h

-75.9 to -75.0

Nucleus

-c

7.7i

-c

Mitochondrion

-0.360d

8j

-78.3

Endoplasmic reticulum

-0.185 to -0.133e

7.2k

-69.7 to -66.2

Vacuole

> +0.769f

6.2l

> -9.2

  1. a. [30] (Homo sapiens). b. The lower and upper values are taken from [32] and [31], respectively. c. The state of the GSSG/GSH couple in the nucleus is thought to be more reduced than in the cytoplasm [40] (see text). d. [33] (Homo sapiens HeLa [34] cells). e. [2] (Mus musculus: mouse hybridoma cells [35]). f. Calculated by combining the law of mass action for Fe+3 + e- ⇌ Fe+2 using standard molal Gibbs energies taken from Ref. [65] with . g. [36] (Homo sapiens). h. [37] (yeast). i. [66] (organism unspecified). j. [38] (HeLa) k. [67]. l. [1]. m. Values of Eh and pH listed here were combined with Eqn. (5) at T = 25°C, P = 1 bar and = 1 to generate the values of log .