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Table 1 Subcellular isoforms of glutaredoxin, thioredoxin and thioredoxin reductase in yeasta.

From: Calculation of the relative metastabilities of proteins in subcellular compartments of Saccharomyces cerevisiae

Protein

SWISS-PROT

Location

Length

Formula

Z

  

Glutaredoxin

    

GLRX1

P25373

Cytoplasm

110

C549H886N146O170S4

-4565

-5.8

-0.182

GLRX2

P17695

Mitochondrion

143

C715H1161N181O213S5

-5617

0.1

-0.255

GLRX3

Q03835

Nucleus

285

C1444H2195N371O463S10

-12031

-24.5

-0.094

GLRX4

P32642

Nucleus

244

C1226H1910N316O389S6

-10276

-17.8

-0.140

GLRX5

Q02784

Mitochondrion

150

C762H1200N196O227S6

-5841

-6.1

-0.192

  

Thioredoxin

    

TRX1

P22217

Cytoplasm

102

C502H785N123O150S5

-3969

-3.1

-0.211

TRX2

P22803

Cytoplasm

103

C497H780N122O153S5

-4056

-3.1

-0.197

TRXB1

P29509

Cytoplasm

318

C1509H2412N402O471S12

-12330

-4.7

-0.159

TRX3

P25372

Mitochondrion

127

C651H1049N167O181S10

-4617

4.9

-0.255

TRXB2

P38816

Mitochondrion

342

C1640H2615N449O501S14

-12841

-1.5

-0.145

  1. a. Amino acid compositions of subcellular isoforms of glutaredoxin (GLRX), thioredoxin (TRX) and thioredoxin reductase (TRXB) in S. cerevisiae were taken from the SWISS-PROT database [64] (accession numbers shown in the table). Chemical formulas of nonionized proteins, and calculated standard molal Gibbs energy of formation from the elements (, in kcal mol-1 at 25°C and 1 bar) and net ionization state (Z) at pH = 7 of charged proteins are listed. Average nominal oxidation state of carbon () was calculated using Eqn. (6).