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Figure 4 | BMC Systems Biology

Figure 4

From: Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions

Figure 4

Comparison of the fitness of yeast strains upon deletion of genes unique to complex cores and genes unique to attachments. Distributions of strain fitness upon deletion of genes only present in cores (red) and genes only present in attachments (blue) in YPD medium. Genes with a fitness of zero are essential. The fitness values of individual genes are partitioned into four categories: 'strong negative effect' (--), 'moderate negative effect' (-), 'weak or no effect' (0) and 'positive effect' (+). Different shades of red illustrate the percentage of genes in cores (for which we have essentiality data) in the four fitness categories, with deep red corresponding to 100% (337 genes). Different shades of blue illustrate the percentage of genes in attachments (for which we have essentiality data) in the four fitness categories, with deep blue corresponding to 100% (320 genes). Enrichments are given on a log2-scale.

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BMC Systems Biology

ISSN: 1752-0509

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