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Table 1 Summary of the models generated in this study.

From: Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae

Model name

No. of parameters

No. of variables

Description

PKA Model A

5

9

Deterministic model of the PKA module based on Cazzaniga et al [14]

PKA Model B

5

9

PKA Model A with optimized parameter values

PKA Model C

2

3

Simplified PKA module with mass action kinetics

PKA Model D

2

4

Simplified PKA module with Michaelis-Menten kinetics

Simplified cAMP Model A

16

5

Conceptual model of the entire cAMP pathway

Simplified cAMP Model B

18

6

Simplified Model A modified to include Krh proteins

Complete cAMP Model

27

15

Complete model of the cAMP pathway with estimated parameters