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Figure 7 | BMC Systems Biology

Figure 7

From: BowTieBuilder: modeling signal transduction pathways

Figure 7

Signaling pathway inferred from a gene regulatory network. This figure depicts a bow tie inferred from membrane-bound proteins and TFs that were predicted to be active in a gene regulatory network [21]. The proteins in the bottom are the TFs, the proteins at the top are the membrane-bound proteins and the remaining proteins constitute the inferred signaling pathway. Different modules of this pathway are associated with different biological processes, where the core module is associated with exocytosis – a process through which cells direct secretory vesicles out of the cell.

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