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Table 3 Performance comparison for randomly generated instantaneously random PBNs.

From: Intervention in gene regulatory networks via greedy control policies based on long-run behavior

Control policies

p b

 

0.1

0.3

0.5

0.7

0.9

ORG

0.8939

0.6934

0.4997

0.2967

0.1063

MFPT

0.8567

0.5807

0.3484

0.1912

0.0747

BOA

0.8595

0.5966

0.3662

0.2026

0.0784

SSD

0.8547

0.5637

0.3349

0.1822

0.0728

CSSD

0.8525

0.5439

0.2971

0.1670

0.0723

  1. Average over 1000 randomly generated PBNs before and after applying all of four control policies: ORG – original stationary mass for undesirable states before control; MFPT – mean-first-passage-time control policy; BOA – BOA control policy; SSD – steady-state distribution control policy; CSSD – conservative SSD control policy with x10 as the control gene.