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Figure 10 | BMC Systems Biology

Figure 10

From: An approach to evaluate the topological significance of motifs and other patterns in regulatory networks

Figure 10

The impact of the coherence between the genes in the pattern instances with the highest topological significance in the transcription networks. Edge weights denote the impact of an individual edge for sustaining the pairwise connections between genes. In all three pattern instances, the intrinsic edges themselves fail to reproduce the impact as accomplished by their common elimination. The summarized effects of their separate removal are significantly lower as compared with the simultaneous deletion of the relation between the respective genes. Hence, these pattern instances affect only as whole entities those gene pairs that are linked by several alternative paths.

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