Figure 5

Condition specific clustering in the chemotaxis and flagellar system in E. coli. (a) Operons encoding the proteins of the chemotaxis and flagellar system in E. coli. The underlined genes belong to operons activated by FlhDC but have additional promoters activated by FliA. They are expressed partially as class 2 genes and fully as class 3 genes. Table and data after [22]. Genes belonging to module 12 are indicated in red, to module 18 in green, to module 24 in blue and to module 45 in magenta. (b) Pairwise clustering frequencies in the LeMoNe clustering ensemble [8, 9] for the flagella genes. Each row/column corresponds to a gene in one of the flagella modules and the heat map value at position (i, j) is the frequency with which gene i and j cluster together. The blocks along the diagonal correspond to respectively module 12, 18, 24 and 45. In module 24, it can be seen that the coclustering frequencies of flhD with the other members is rather low, indicating a weaker degree of coexpression. See also Supplementary Figure S5.