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Figure 4 | BMC Systems Biology

Figure 4

From: Comparative analysis of module-based versus direct methods for reverse-engineering transcriptional regulatory networks

Figure 4

Regulator specific comparison of LeMoNe and CLR on S. cerevisiae. For each regulator in S. cerevisiae with known interactions inferred: (a) the number of interactions in the reference network (green) and the number of true positives in LeMoNe (red) and CLR (blue); (b) the number of interactions inferred (green) and the number of true positives (red) in LeMoNe, and the number of interactions inferred (yellow) and the number of true positives (blue) in CLR. LeMoNe and CLR networks are both cut off at the first 1070 predictions. Regulators are sorted by the difference TPLeMoNe – TPCLR. The total number of true positives is 40 for LeMoNe and 31 for CLR. For clarity, the x-axis in (a) is truncated, the true number of targets for GCN4 is 120. The number of interactions inferred only counts targets that belong to the reference network.

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