Figure 11
From: miRNA-regulated dynamics in circadian oscillator models
Effect of variation of the rate of binding of miRNA to mRNA (c 3 ) on the PER protein for Model B. Variation of (a) the frequency and (b) the amplitude of oscillation in the PER protein as a function of c3, the rate of binding of the miRNA to mRNA. Cases 1 and 2 are shown in blue and red respectively. The other parameters, namely the miRNA production rate (c1) and RISC degradation rate (c4) are kept fixed at 0.05 h-1 and 0.001 h-1 respectively.