Skip to main content
Figure 1 | BMC Systems Biology

Figure 1

From: Reconstruction of Escherichia coli transcriptional regulatory networks via regulon-based associations

Figure 1

Activity profile of ArgR, TrpR, Lrp and LexA. Several conditions in our data set were expected to elicit transcriptional responses mediated by the activity of known regulators. We found that in all conditions with well-studied and understood transcriptional responses, the identity of the most active TF matched our expectations. For example, in an experiment which was conducted to measure transcriptional response to addition of the amino acid arginine, transcription factor ArgR appeared to be the most active TF. Similarly, TrpR was the most active TF in the condition when tryptophan was added to the medium, and LexA was the most active TF under conditions of UV and Gamma treatment.

Back to article page