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Figure 2 | BMC Systems Biology

Figure 2

From: Identifying disease-specific genes based on their topological significance in protein networks

Figure 2

Co-occurrence with the word "psoriasis" for differentially expressed genes as a fraction of total number of PubMed hits. Due to the high interconnectivity of biological networks, many differentially expressed genes are also part of the shortest path network and were therefore assigned a p-value. Genes that are both differentially expressed and scored highly for network topology show the most relevance and specificity to psoriasis. Figure 1b shows that results presented here are not simply due to the fact that genes with small p-values are also the best studied.

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