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Table 4 Evaluation of prediction method variants using LOCSCL

From: Protein-protein interaction as a predictor of subcellular location

PPI sets

DISCRETE

MERGED

COMMON

MAJORITY

 

PA

SA

PA

SA

PA

SA

PA

SA

Reference

0.70

0.34

0.76

0.32

0.73

0.36

0.75

0.36

ALL

0.71

0.43

0.82

0.45

0.79

0.52

0.79

0.48

BIO

0.76

0.48

0.78

0.43

0.77

0.50

0.78

0.48

EVI

0.72

0.38

0.83

0.39

0.81

0.43

0.78

0.43

  1. The four methods were applied to PPIs where one protein has a known SCL and the other SCL is unknown, generating new SCL predictions for the previously unlocated proteins. Permissive (PA) and strict accuracy (SA) were calculated based on the newly available SCL data for these proteins.
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BMC Systems Biology

ISSN: 1752-0509

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