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Figure 7 | BMC Systems Biology

Figure 7

From: Detecting coordinated regulation of multi-protein complexes using logic analysis of gene expression

Figure 7

Sub network of AND relations between the ribosome, energy, transcription and translation related complexes. The sub-network was derived using all AND triplets that involve complexes associated with the ribosome (small and large subunits). Each group of complexes in the same functional class, as defined by MIPS functional categories [19], is colored differently. The arrow next to the functional classes represents the regulatory state of the subunits of the complexes: green - mRNA repressed, red - mRNA induced. Complexes in the "Transcription" category are the RNA polymerases I, II and III. Complexes in the "Translation" category are eIF2, eIF2B, eIF3, eIF4F translation initiation factors and GCN1-GCN20 regulate the translation elongation. Complexes in the "Energy" category are cytochrome bc1, cytochrome C oxidase and Succinate dehydrogenase II, all mitochondrial redox carriers.

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