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Table 5 Comparing ranked lists of hub-likeness properties between the classifier and the hypothetical PINs in MRSA252.

From: The use of Gene Ontology terms for predicting highly-connected 'hub' nodes in protein-protein interaction networks

Hub prediction methods

correlation coefficient

Hub classifier

0.320523

Hypothetical PIN – pathway maps

0.108682

Hypothetical PIN – orthologous interactions

0.27396

Hypothetical PIN – interacting domain

-0.291846

Combined hypothetical PIN – (pathway maps + orthologous interactions)

0.23882

Combined hypothetical PIN – (pathway maps + orthologous interactions + interacting domains)

-0.011494

  1. The ranked protein lists based on hub-likeness properties, produced by either the classifier or the hypothetical PINs, has been compared to that of the experimental PIN in MRSA252. The coefficient of Spearman rank order correlation is reported with p-value < 0.05.