Figure 8

The tokenized simulator user interface. (a) The setup window for the tokenized simulator. The simulation is being configured to have two High nodes, EGF and LKB-auto. EGF will be initialized with a token-count of 10, LKB-auto with a token-count of 3. The token-count of AMPK will be zero for the duration of the simulation. (b) The setup window for the differential simulator. Two different scenarios are being compared through simulation: different token assignments are being tried with EGF and LKB-auto, with and without AMPK being fixed low. (c) The plot window for the marking series generated by a simulation. Observe that the signaling nodes whose activity-levels are plotted correspond to those selected in the checklist directly to the left of the plot.