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Figure 3 | BMC Systems Biology

Figure 3

From: Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion

Figure 3

IL6ST rescued AblPP-induced cell de-adhesion. (A) Relative abundance of IL6ST mRNA level in AblPP cells infected by IL6ST shRNA or control shRNA was measured by quantitative PCR. The mRNA level from AblPP cells infected by control shRNA was set as 100. (B) AblPP was induced in AblPP cells infected by IL6ST shRNA or control shRNA by doxycycline addition and cell detachment assay was measured at 4 hours. (C) The knockdown of IL6ST did not affect the expression of AblPP or its kinase activity.

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