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Figure 2 | BMC Systems Biology

Figure 2

From: Extraction of elementary rate constants from global network analysis of E. coli central metabolism

Figure 2

Allosteric enzymes consisting of an allosteric segment (dark shaded area) and an enzymatic reaction segment. (A): Pyruvate kinase, where the number of allosteric sites and catalytic sites are 4 and 1, respectively [39]. (B): Phosphofructokinase, where the number of allosteric sites is 2 according to [39]. Non-integral reaction orders are assumed for two substrates due to fractal properties caused by enzyme conformational changes [43].

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