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Figure 4 | BMC Systems Biology

Figure 4

From: From pathway to population – a multiscale model of juxtacrine EGFR-MAPK signalling

Figure 4

Results of intracellular signalling model. Model predictions – effect of cell contact stability on Erk-PP. Case 1, two cells make an initial small contact of 2 μm, which increases linearly to 23 μm over 6 hours. Case 2 shows the same initial formation pattern, but with an instantaneous break of contact after 4 hours when it has reached 16 μm length. Case 3 shows the signal arising from an 'instantaneously' formed 12 μm contact.

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