From: Identification of functional modules using network topology and high-throughput data
JACS | Size | Front | Enriched GO terms | p-value | TFs | p-value |
---|---|---|---|---|---|---|
1 | 120 | 119 | processing of 20S pre-rRNA | < 0.001 | Fhl1 | 4.82·10-16 |
 |  |  | rRNA processing | < 0.001 | Rap1 | 2.89·10-11 |
 |  |  | 35S primary transcript processing | < 0.001 | Sfp1 | 2.98·10-8 |
 |  |  | ribosomal large subunit assembly and maintenance | 0.019 |  |  |
 |  |  | rRNA modification | < 0.001 |  |  |
 |  |  | ribosome biogenesis | 0.029 |  |  |
2 | 120 | 118 | translational elongation | < 0.001 | Fhl1 | 1.03·10-5 |
3 | 120 | 118 | processing of 20S pre-rRNA | < 0.001 | Â | Â |
 |  |  | rRNA processing | 0.030 |  |  |
 |  |  | 35S primary transcript processing | 0.011 |  |  |
 |  |  | ribosomal large subunit assembly and maintenance | 0.019 |  |  |
 |  |  | ribosomal large subunit biogenesis | < 0.001 |  |  |
5 | 120 | 112 | signal transduction during filamentous growth | 0.010 | Ste12 | 5.41·10-13 |
 |  |  | conjugation with cellular fusion | < 0.001 | Dig1 | 5.41·10-13 |
6 | 120 | 99 | transcription from RNA polymerase III promoter | < 0.001 | Â | Â |
 |  |  | transcription from RNA polymerase I promoter | 0.006 |  |  |
7 | 120 | 107 | ergosterol biosynthesis | < 0.001 | Â | Â |
 |  |  | hexose transport | 0.019 |  |  |
8 | 114 | 85 | chromatin remodeling | 0.050 | Â | Â |
11 | 120 | 114 | pseudohyphal growth | 0.010 | Msn2 | 3.17·10-4 |
 |  |  | response to stress | < 0.001 | Msn4 | 1.82·10-12 |
14 | 120 | 102 | ubiquitin-dependent protein catabolism | 0.047 | Â | Â |
15 | 120 | 96 | nuclear mRNA splicing, via spliceosome | < 0.001 | Â | Â |
16 | 89 | 61 | ubiquitin-dependent protein catabolism | < 0.001 | Rpn4 | 6.44·10-6 |
17 | 120 | 109 | response to stress | < 0.001 | Msn4 | 1.74·10-3 |
 |  |  | mitochondrial electron transport | < 0.001 |  |  |
18 | 87 | 59 | nuclear mRNA splicing, via spliceosome | 0.012 | Â | Â |
20 | 46 | 35 | pyridoxine metabolism | 0.045 | Â | Â |