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Table 3 Leukocyte receptors, their corresponding ligands, and their allowed behaviors

From: Dynamics of in silico leukocyte rolling, activation, and adhesion

Leukocyte Receptor

Surface Receptor-Ligand

Behaviors

PSGL-1

P-Selectin

Rolling

VLA-4 Integrin

VCAM-1

Rolling, Firm Adhesion

CXCR-2 Chemokine Receptor

GRO-α Chemokine

Activation

  1. These three receptor-ligand pairs were chosen because together they are sufficient for enabling leukocytes to roll, become activated, and firmly adhere in vitro.
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BMC Systems Biology

ISSN: 1752-0509

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