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Volume 10 Supplement 3

Selected articles from the International Conference on Intelligent Biology and Medicine (ICIBM) 2015: systems biology

Research

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Indianapolis, IN, USA13-15 November 2015

Edited by Zhongming Zhao, Yunlong Liu, Yufei Huang, Kun Huang and Jianhua Ruan.

Related articles have been published in a supplement to BMC Genomics.

  1. The 2015 International Conference on Intelligent Biology and Medicine (ICIBM 2015) was held on November 13–15, 2015 in Indianapolis, Indiana, USA. ICIBM 2015 included eight scientific sessions, three tutorial ...

    Authors: Zhongming Zhao, Yunlong Liu, Yufei Huang, Kun Huang and Jianhua Ruan
    Citation: BMC Systems Biology 2016 10(Suppl 3):61
  2. The high degree of heterogeneity observed in breast cancers makes it very difficult to classify the cancer patients into distinct clinical subgroups and consequently limits the ability to devise effective ther...

    Authors: Suleyman Vural, Xiaosheng Wang and Chittibabu Guda
    Citation: BMC Systems Biology 2016 10(Suppl 3):62
  3. Computer-aided, interdisciplinary researches for biomedicine have valuable prospects, as digitalization of experimental subjects provide opportunities for saving the economic costs of researches, as well as pr...

    Authors: Rudong Li, Hui Cheng, Tao Cheng and Lei Liu
    Citation: BMC Systems Biology 2016 10(Suppl 3):64
  4. Cancer is increasingly recognized as a cellular system phenomenon that is attributed to the accumulation of genetic or epigenetic alterations leading to the perturbation of the molecular network architecture. ...

    Authors: Feixiong Cheng, Chuang Liu, Bairong Shen and Zhongming Zhao
    Citation: BMC Systems Biology 2016 10(Suppl 3):65
  5. The advance in targeted therapy has greatly increased the effectiveness of clinical cancer therapy and reduced the cytotoxicity of treatments to normal cells. However, patients still suffer from cancer relapse...

    Authors: Yu-Ching Hsu, Yu-Chiao Chiu, Yidong Chen, Tzu-Hung Hsiao and Eric Y. Chuang
    Citation: BMC Systems Biology 2016 10(Suppl 3):66
  6. Information about drug–drug interactions (DDIs) supported by scientific evidence is crucial for establishing computational knowledge bases for applications like pharmacovigilance. Since new reports of DDIs are...

    Authors: Yaoyun Zhang, Heng-Yi Wu, Jun Xu, Jingqi Wang, Ergin Soysal, Lang Li and Hua Xu
    Citation: BMC Systems Biology 2016 10(Suppl 3):67
  7. Recently, structured sparse canonical correlation analysis (SCCA) has received increased attention in brain imaging genetics studies. It can identify bi-multivariate imaging genetic associations as well as sel...

    Authors: Lei Du, Heng Huang, Jingwen Yan, Sungeun Kim, Shannon Risacher, Mark Inlow, Jason Moore, Andrew Saykin and Li Shen
    Citation: BMC Systems Biology 2016 10(Suppl 3):68
  8. Technological advances in medicine have led to a rapid proliferation of high-throughput “omics” data. Tools to mine this data and discover disrupted disease networks are needed as they hold the key to understa...

    Authors: Ying-Wooi Wan, Genevera I. Allen, Yulia Baker, Eunho Yang, Pradeep Ravikumar, Matthew Anderson and Zhandong Liu
    Citation: BMC Systems Biology 2016 10(Suppl 3):69
  9. Driving Boolean networks to desired states is of paramount significance toward our ultimate goal of controlling the progression of biological pathways and regulatory networks. Despite recent computational deve...

    Authors: Rongjie Liu, Chunjiang Qian, Shuqian Liu and Yu-Fang Jin
    Citation: BMC Systems Biology 2016 10(Suppl 3):70
  10. Glioma is the most common brain tumor and it has very high mortality rate due to its infiltration and heterogeneity. Precise classification of glioma subtype is essential for proper therapeutic treatment and b...

    Authors: Sujuan Wu, Junyi Li, Mushui Cao, Jing Yang, Yi-Xue Li and Yuan-Yuan Li
    Citation: BMC Systems Biology 2016 10(Suppl 3):71